Dinonyl phthalate 84-76-4
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Dinonyl phthalate, a phthalate derivative and organic extract contaminant found in drinking water, has been shown to activate Nrf-2-mediated antioxidant responses in human cell lines.
| chemical properties | Clear yellow-brown oily liquid |
| use | Dinonyl phthalate, a phthalate derivative and organic extract contaminant found in drinking water, has been shown to activate Nrf-2-mediated antioxidant responses in human cell lines. |
| general instructions | Colorless and odorless liquid. |
| air and water reaction | Flammable. Hydrolyzed by strong mineral acids and strong bases. |
| reactive profile | Dinonyl phthalate is an ester. The ester reacts with the acid, releasing heat along with the alcohol and acid. Strong oxidizing acids may cause a violent reaction that is sufficiently exothermic to ignite the reaction products. The interaction of the ester with the caustic solution also generates heat. Esters mixed with alkali metals and hydrides can produce flammable hydrogen gas. Can generate an electrostatic charge [Safe Handling of Chemicals, 1980. 250]. |
| health hazard | Moderately toxic if swallowed. |
| Purification method | The ester was washed with aqueous Na2CO3 solution and shaken with water. Diethyl ether was added to break the emulsification, and the solution was washed twice with water and dried (CaCl2). After evaporating the diethyl ether, the residual liquid was distilled three times under reduced pressure. Store it in a vacuum desiccator over P2O5. [Beilstein 9 IV 3183. ] |
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